Beginning with its founding in 1803, Worthington educated students in paid subscription schools. An 1825 Ohio law enacted property taxes to support public education, and two Sharon Township one-room schools were established on the north and south sides of the Village of Worthington. 

According to historian Jennie McCormick in her book "Two Centuries of Educational History: Worthington Ohio," Worthington established a village school district in 1854, with a board of education separate from Sharon Township. In 1875, a consolidated Worthington School with the first high school classes was built. McCormick writes that "Teacher/principal C.H. [Charles Henry] Crandell is the first to be titled 'superintendent'." As reported in the "Columbus Dispatch," Crandell moved to Illinois in August, 1882.

Through the decades, Worthington's superintendents have managed the growth and operation of the school system from a single building with two high school graduates in 1880, to a district that serves over 10,000 students through 21 academic programs and schools. 

Daniel W. Wright, 1891-1892
Harvey S. Gruver, 1900-1908
Henry C. Fickell, 1911-1921
Vance M. Smith, 1921-1924
Cleon E. Webb, 1929-1936
Donald S. Wickerham, 1936-1938
Harold C. McCord, 1938-1973
Dr. Dana F. Swick, 1973-1975
Dr. Edward R. Lakey, 1978-1984
John W. Hoeffler, 1984-1990
Damon Asbury, 1991-2000
Rick E. Fenton, 2000-2005
Melissa Conrath, 2006-2011
Thomas Tucker, 2011-2015